It's her eyes themselves that are "off" IMO. The cornea whites appear greyish blue, and the stare is glassy making her appear "robotic". The iris and it's reflections are very well done.

Actually, I'm amazed at how well you did with a CG image. Her pores and lips are spot on. You did a phenominal job and I only wish my editing skills were 10% of the talent you show. Kudos!

EDIT: wow, I just checked out the full sized version in your port and she's amazing. Torso, breasts, tanlines, legs, are killer! Her right arm (left facing) between the elbow and shoulder looks to be "off" just a mite, and her hair sits the head like a wig, but otherwise I'd be hard pressed not to have thought you had shot a real woman. I'm in awe and bow at your talent level, oh Yoda Master! 

I'm no 3D artist, either, but the things which stand out to me are:

The eyes.  As said, they just don't fit the scene / mood / model.  As if they're being rendered as a glass surface when they should be opaque with a thin reflective (mostly transparent) coating.  Corneas are also a bit too distinct.

Inner edge of right nostril - sharp; looks as if the inside of the nostril is being lit or is empty and being filled in by the renderer.

Lips - they shouldn't come together so neatly; there should be some imperfection to their meeting which is either not present or not represented well by this frame.  I'm also used to seeing lips this size have a more accented protrusion from the face generally - not necessarily coming out further, but coming out faster where they do.  Could just be the lighting angle.

Left side jawline - could be JPEG artifact; could be LOD of the render, but there looks to be some polygonal corners protruding.

If going for a hyper-real look, a few light creases and 'body' to the skin would do the trick.

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Like I said, I wish I could do what you did, but fwiw those are the things I'd be noticing if I managed to get this far.

Kevlar Vest Girl wrote:

The face is darker than the neck.

If you lived around here you'd be used to that.  Sunless tanner is expensive! 

You keep saying "she looks stoned" like that's a bad thing.

A permanently stoned chick that isn't human?

I feel like I'm back in Hollywood again.

She's only about 2 weeks old, so she is to young to be getting stoned ... even if she were in Hollywood. Tommy, that makes her too young to date... Sorry.

I also kinda thought the black speckles looked like flaking mascara, so I wasn't too upset about it. It is actually a flaw in one of the 4 layers that make up her skin. Sadly I'm not all that sure which one... I'll find it. I kniow that makes me sound kinda stupid. Each map needs to be put in with its own numbers.
like for example if the depth map is put in with numbers too low, it will have no effect. If it is given too high a value, then she will look spiky.
finding a balance between the color, bump, UV, and texture maps is a little tricky and I'm working on it.

I'm thinking I'm having an issue with how the "lights" react.
As photographers we know the effects of large and small, close and distant lights.
I'm seeing a lot of harsh shadowing.
If it was in the real world I could just change the distance of the light.

I can't do that in this software.
There are raytraced and depthmap lighting ... blah blah ... I just have to figure out how that translates into real world effects.

Of course once I have the light spreading and bouncing in all the happy ways I want it to ... I'm sure I'll have to readjust the maps.   

I also think I went overboard with the shiny nose. The shine goes too high.
The good thing is that is it's own map.
A map that is probably totally unnecessary.
I just wanted to give her a little oiliness to her forehead and a little shine to her nose. Things that most of the women in our lives do their best to get rid of. I just thought it gave her a little more human quality.
that's the same reason she has freckles and I have thought about giving her a mole.

Thank you guys for your input, I'm trying to work out the problems as you tell me. Keep it coming.

I'm going to see what kind of things I can do with the lights
Thanks for the clue